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Human Organ Models

Explore Revivocell's NANOSTACKS™-based microphysiological systems—modular, human-relevant organ models for predictive toxicity, efficacy, and mechanistic biology.

Revivocell builds human microphysiological systems (MPS) using the modular NANOSTACKS™ platform. Our organ models enable multicellular, physiologically relevant studies of drug safety, metabolism, and organ crosstalk.

Each model is available as a standalone product for in-house use or as part of our fully managed contract research services.

Liver Microphysiological Systems

Our liver models span from simple monocultures to complex immune-competent systems, enabling investigation of hepatotoxicity, metabolism, fibrosis, and inflammation-driven liver injury.

Liver Monoculture MPS

Liver Monoculture MPS

Primary Human Hepatocytes

  • Hepatotoxicity screening
  • Metabolic stability studies
  • Long-term hepatocyte function
  • CYP450 activity assessment
Liver Triculture MPS

Liver Triculture MPS

Hepatocytes + Endothelial + Stellate

  • Stromal & vascular modulation
  • Fibrosis mechanisms
  • Microenvironment interactions
  • Chronic exposure studies
Liver Tetraculture MPS

Liver Tetraculture MPS

Immune-Competent Liver Model

  • Immune-hepatic crosstalk
  • Inflammation-driven toxicity
  • Fibrosis & immune modulation
  • DILI & immune mechanisms

Brain Microphysiological System

Our Brain MPS enables both structural and functional neurotoxicity assessment using human-relevant neural configurations.

Structural Neurotoxicity

Astrocyte-Neuron Co-Culture

  • Neurite outgrowth analysis
  • Morphological assessment
  • Imaging-based readouts
  • Early hazard identification

Functional Neurotoxicity

iPSC-Derived Neural Networks

  • MEA-based functional readouts
  • Network activity analysis
  • Seizure liability assessment
  • AI-ready datasets

Multi-Organ Microphysiological System

The Multi-Organ MPS enables investigation of inter-organ crosstalk, systemic toxicity, and organ-to-organ signaling using stackable NANOSTACKS™ modules.

Supported Organ Modules

  • Liver (mono-, tri-, tetraculture)
  • Brain (structural & functional)
  • Gut & intestinal barrier
  • Immune-relevant compartments
  • Custom organ configurations

Key Applications

  • Liver-brain axis modeling
  • Systemic toxicity assessment
  • Organ crosstalk mechanisms
  • Multi-organ ADME studies
  • Inflammation & immune responses

Product or Service? You Decide.

All organ models are available as standalone products for in-house research or as part of our fully managed contract research services.

Buy the Platform

Purchase NANOSTACKS™-based organ models for in-house use. Ideal for labs with expertise in MPS or those building internal capabilities.

  • Full experimental control
  • Flexible study design
  • Compatible with standard lab equipment
  • Training and support available

Fully Managed Studies

Let Revivocell's scientific team design, execute, and interpret your toxicity studies. Ideal for decision-ready data without internal setup.

  • Expert study design
  • Full execution by our team
  • Decision-ready reporting
  • No equipment or training needed

Ready to Build Your Model?

Contact our scientific team to discuss your research needs and find the right organ model configuration.

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