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NANOSTACKS™ Technical Datasheet

Complete specifications and detailed information for the NANOSTACKS™ platform

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NANOSTACKS Technology Illustration

Key Technical Specifications

Platform typeModular organ-on-chip / microphysiological system (MPS)
Plate format24-well SBS-standard
Body materialMedical-grade polycarbonate (PC)
Membrane materialPolyester (PETE), 10 µm thickness
Membrane pore size0.4 µm (standard)
StackabilityUp to 4 modular levels per well
Working volume0.5–1.5 mL per well
Culture conditionsStatic or orbital shaker–based flow
Imaging compatibilityWidefield and confocal microscopy
SterilitySupplied sterile, ready-to-use

Detailed Specifications

Cell growth area0.28 cm² per level
Alternative pore sizes0.1, 0.2, 1, 3, 5, 8 µm (available on request)
Validated culture duration≥28 days (primary human cells)
Barrier model compatibilityYes (ALI-STACK compatible)
Material characteristicsPDMS-free, low drug adsorption, imaging-compatible
Intended useResearch use only (RUO)

Platform Features

Modular Architecture

Stack up to 4 discrete compartments per well to create physiological microenvironments and control cell-cell communication.

Standard Format Compatibility

Fits seamlessly into standard 24-well SBS-format plates for integration with existing laboratory workflows.

Imaging-First Design

Compatible with widefield and confocal microscopy for live-cell imaging and high-content analysis.

Physiological Relevance

Validated for ≥28 days of culture with primary human cells, supporting long-term, relevant in vitro studies.

Assay Compatibility

Microscopy & Imaging

  • Fluorescence microscopy
  • Confocal imaging
  • Automated high-content screening
  • Live-cell analysis

Plate Reader Assays

  • Colorimetric readouts
  • Fluorometric assays
  • Luminescent endpoints
  • Kinetic measurements

Molecular Analyses

  • ELISA & immunoassays
  • Mass spectrometry
  • qPCR & genomics
  • Biomarker profiling

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