Our technology
Our technology
Explore our flagship technology NANOSTACKSTM and our other solutions for the developement of complex, user-friendly multicellular in vitro models.
NANOSTACKS™: Revolutionizing in-vitro modeling for advanced research and drug discovery
Our revolutionary platform NANOSTACKSTM allows the development of complex in vitro models with ease, as both cell-cell and organ-organ interactions can be modeled whilst maintaining compatibility with standard laboratory equipment.”
NANOSTACKSTM readouts
Imaging
Including imaging-based assays, such as neurite outgrowth assays
Differentiated SH-SY5Y on NANOSTACKSTM
Plate reader-based assays
Perform easily viability, proliferation, cytotoxicity assays and more
Cytotoxicity of Zileutone (High-DILI-Concern) on primary human hepatocytes (PHH) on NANOSTACKSTM
Downstream sampling of medium and cells
Compatibility with assays such as ELISA and PCR
Albumin levels in primary human hepatocytes (PHH) on NANOSTACKSTM
Unique Benefits
Versatile 3D Assembly
Complex physiologically relevant tissue structures can be created by assembling up to 4 NANOSTACKS™ in one well
Intercellular communication
Cell-cell crosstalk between cells is replicated in the platform, increasing its similarity to the in vivo environment
Industry-Compliant Design
The 24-well plate format allows the execution of a wide variety of assays
Ease of imaging
The platforms are transparent, simplyfing their imaging
Easy to use
Cell culture on NANOSTACKSTM is straightforward
Scalable and Cost Effective
Scale up tissue models cost-effectively with NANOSTACKS™, offering an alternative to expensive microfluidic chip methods
NANOSTACKSTM specifications
| Well-plate compatibility: | SBS-standard 24-well plate |
|---|---|
| Membrane pore size: | 0.4 µm *other pore sizes available on request |
| Membrane material: | Transparent PET or PC |
| Cell growth area: | 0.28 cm2 |
| Working volume: | 0.5 - 1.5 mL |
To model multiple barriers in a single in vitro model, we developed our CELLBLOKS® platform. Assemble different BLOKS into a 12-well plate to build the complex in vitro model of your choice.
The Platform
The CELLBLOKS® platform has the dimensions of a SBS-standard tissue culture plate. It has four separate channels, each capable of housing three separate Blocks. Each channel is filled with media (3-5 ml) to allow cell-cell communication between the Blocks.
Need some help?
If you're interested in discovering how our organ models can benefit your research, we invite you to get in touch with us. Our team is available to provide further insights and address any inquiries you may have.
Contact information
UK
USA
BioLabs@NYU LANGONE, 180 Varick St, Floor 6, New York, NY 10014
info@revivocell.com
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