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Innovative Organ-on-a-Chip (OOAC) technology to improve research in human health and enhance drug discovery
We want to enable scientists to be more creative in their research by proving next dimension cell culture technology, which is easy to use and interactive, whilst closely mimicking body-like conditions and reducing animal testing. Current conventional culture plates & petri-dish approaches are static and self-limiting. Cells are grown in isolation that simply do not represent the real nature of human cell-cell interactions. Whereas, current organ-on-a-chip technologies are difficult to use, have limited throughput and require significant investment
Our novel patented platform, CELLBLOKS®, is a multi-organ/cell type modular “plug and play” Organ-on-a-Chip technology that emulates the organ microenvironments in a standard in-vitro setting. The technology offers researchers a novel way to better predict human responses to new drugs, cosmetics, foods and viruses
"For biological research or drug discovery applications, striving towards organotypic structure and function will improve the translational relevance and predictivity of cell models. 3D assembly of multi-cellular structures, communication between cells within or across connected models alongside media flow are the focus of multiple organ on a chip (OOAC) technologies.
CELLBLOKS is a new entry into the OOAC space. It has plate-based familiarity with the potential to develop and connect multiple cell models exploiting the multi-modular nature of the technology. Established cell or trans-well based models can be migrated into the format and connected in multiple combinations with or without media flow. The approach exploits existing laboratory equipment and requires minimal training, enabling a lower barrier to investment and reduced model transition to the format compared to other approaches on the market."
"CELLBLOKS® is a true innovation for co-culture activities. The soluble factors including growth factors and cytokine can be smartly and conveniently introduced to targeted cellular population in a semi-quantitative manner. The working procedure is simple and easily implemented."
“CELLBLOKS® is great technology and innovative technique. Very easy to use and instructions are well designed. This platform enables us to screen various compounds in-vitro during our research using nanoparticles, aptamers, and others. We are interested to better mimic skin barrier and blood brain barrier and are continuing to explore the use of CELLBLOKS® for this purpose. Our research continues in this filed, to discover new products we would need models like CELLBLOKS® for testing permeation and penetration of cell lines. I would recommend it and encourage other researchers to use it.”
"CELLBLOKS® can be used to overcome the serious limitations hampering the use of organotypic slice cultures in long-term experiments. The system allows sharing of cell secreted factors released from three or more types of cross-communicating cells/tissues and can be easily adapted in studying cell-cell interactions in complex organs like the salivary glands."
A single platform allowing the study of cell-cell interactions in real-time
CELLBLOKS® 3D stack Liver-on-a-Chip model
This models contains 24 individual liver-chips per plate. Each chip consists of multiple liver cell types grown in layered scaffold blocks, arranged in close proximity in a 3D stacked format and is ready to be exposed to test drugs
CELLBLOKS® 2D layout Liver-on-a-Chip model
This CELLBLOKS® kit contains readily grown physiological relevant liver micro-tissues constituting different cell types of the liver grown adjacent to each other enabling in-vivo relevant cell-cell iterations constituting metabolic function essential for predicting adverse drug effects in your lab
Use CELLBLOKS® kits to build your own unique organ models in your lab
CELLBLOKS® is unique because no other plate platform allows you to study complex in-vivo like cell-cell interaction studies with ease. Using CELLBLOKS® you can build complex models by simply putting together different cell growth Blocks in one platform that are designed to mimic both barrier organs and those in systematic circulation